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Serine is an essential amino acid from which the body forms proteins. Serine is a precursor in the production of purines and pyrimidines. It is also a component of serine proteases such as trypsin or chymotrypsin.

Serine also serves as a starting substance for the synthesis of phosphatidylserine, a membrane lipid. Phosphaditylserine is a natural cortisol brake even for alcoholics who are equally swimming in cortisol.

There is evidence that a deficiency of D-serine may play a role in the development of depression.

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