Skip to content

Metabolic effects of glutamine on insulin sensitivity

Glutamine, the most abundant free amino acid in human plasma, has excellent nutritional and non-nutritional properties. Glutamine regulates immune function and modulates cellular metabolism. In particular, its administration in various experimental and clinical studies showed a positive effect on glucose oxidation and on insulin resistance.

In humans, glutamine acts both as a substrate and as a modulator of its metabolism to glucose. In trauma patients and in critical illness, parenteral glutamine supplementation improved insulin sensitivity and increased the release of insulin by pancreatic β-cells. Also, in a recent clinical trial, oral L-glutamine supplementation improved the glucose profile in patients and subjects with type 2 diabetes.

The mechanisms underlying these specific effects are still unknown. Several diseases, such as obesity and diabetes, could receive important benefits from glutamine supplementation, possibly in conjunction with conventional therapy.


Metabolic effects of glutamine on insulin sensitivity (pdf file)

Found at Alkohol adé (german)

Powered by BetterDocs

Close Popup

Bye bye booze needs a few cookies, too.

However, we try only to activate as few as possible technically necessary cookies so that your visit to this site cannot be tracked as far as possible by third parties. We do not share any information about your visit with anyone.

But even we we do need a few - e.g. to display this legal notice or to care for that you do not have to log in again for each page or see this popup again for each page.

As soon as you click on an external link or video, cookies may be set by the operators of these sites, which we cannot influence. Learn more on our privacy page.


Close Popup