Skip to content

Glutamic acid and ethanol dependence

Glutamic acid and ethanol dependence

Glutamate diethyl ester, a specific glutamate antagonist, attenuated the seizures and decrease in behavioral activity observed in mice during withdrawal. Before withdrawal, ethanol-dependent animals were hypersensitive to kainic acid, a potent glutamate agonist, but they were not hypersensitive to the anticonvulsant pentylenetetrazol.

These findings suggest that hypersensitivity to glutamate develops during ethanol dependence and that this phenomenon contributes to the signs of ethanol withdrawal.


Pharmacology Biochemistry and Behavior | Glutamic acid and ethanol dependence

Found at Alkohol adé (german)

Powered by BetterDocs

This site is still under development. Feel free to look around and don't hesitate to give us feedback, you'll find a form at the end of each page.

Nevertheless, we activate a few cookies, and these cookies could change due to the fact. that it's a development-site.


Bye bye booze needs cookies, too. However, we try only to activate as few as possible technically necessary cookies so that your visit to this site cannot be tracked as far as possible by third parties.

 

However, we do need a few - e.g. to display this legal notice or to care for that you do not have to log in again for each page or see this popup again for each page.

 

As soon as you click on an external link or video, however, cookies may be set by the operators of these sites, which we cannot influence. Learn more on our privacy page.