Skip to content

Effect of alcohol on sleep and nighttime plasma growth hormone and cortisol concentrations

The acute and chronic effects of alcohol and alcohol withdrawal on sleep behavior and plasma GH and cortisol fluctuations occurring during sleep were studied.

Five healthy men aged 21-26 years consumed a placebo drink for 3 nights, alcohol (0.8 g/kg) for 9 nights, and a placebo drink on the last night of withdrawal. Throughout the night, polygraphic sleep recordings and blood samples (taken every 20 minutes with a venous catheter) were obtained for 1 placebo, 1 acute alcohol, 1 chronic alcohol (night 9), and 1 alcohol withdrawal night.

Acute and chronic alcohol consumption did not significantly decrease rapid eye movement sleep in the first half of the night, whereas slow wave sleep (stages 3 and 4) was significantly increased after acute alcohol and returned to baseline values on the night of chronic alcohol withdrawal. On the night of withdrawal, rapid eye movement sleep and slow wave sleep were not significantly different from placebo sleep. Alcohol significantly suppressed plasma GH levels (70-75%) on acute and chronic nights.

All measures of GH, including total integral for sleep time, mean hourly rate, and peak rate, were similarly affected by alcohol. On the withdrawal night, GH values returned to placebo values. Measurements of nocturnal plasma cortisol were not significantly altered by alcohol or alcohol withdrawal at this dose level.

J Clin Endocrinol Metab.: Effect of alcohol on sleep and nighttime plasma growth hormone and cortisol concentrations

Found at Alkohol adé (german)

Powered by BetterDocs

Close Popup

Bye bye booze needs a few cookies, too.

However, we try only to activate as few as possible technically necessary cookies so that your visit to this site cannot be tracked as far as possible by third parties. We do not share any information about your visit with anyone.

But even we we do need a few - e.g. to display this legal notice or to care for that you do not have to log in again for each page or see this popup again for each page.

As soon as you click on an external link or video, cookies may be set by the operators of these sites, which we cannot influence. Learn more on our privacy page.

Close Popup