Bye bye, booze!
The aim of this thesis is to investigate the methylation of the dopamine transporter (DAT) promoter at the onset ofThe aim of this thesis is to investigate the methylation of the dopamine transporter (DAT) promoter at the onset of alcohol withdrawal in order to identify possible links between alcohol dependence and craving. Craving is the strong desire for a substance such as alcohol – in banal terms also “binge drinking”.
At the beginning of alcohol withdrawal, venous blood was taken from the patients and the DNA contained therein was examined for specific methylation of the DAT promoter. Significantly higher methylation of the DAT promoter was found compared to the healthy control group.
This indicates that alcohol dependence led to hypermethylation of the DAT promoter and could ultimately be responsible for a reduction in craving.
Alcohol dependence and the specific methylation of the dopamine transporter gene (german)
Found at Alkohol adé
Powered by BetterDocs
(Use Cropper to set image and use mouse scroller for zoom image.)
Already have an account? Login
This site is still under development. Feel free to look around and don't hesitate to give us feedback, you'll find a form at the end of each page.
Nevertheless, we activate a few cookies, and these cookies could change due to the fact. that it's a development-site.
Bye bye booze needs cookies, too. However, we try only to activate as few as possible technically necessary cookies so that your visit to this site cannot be tracked as far as possible by third parties.
However, we do need a few - e.g. to display this legal notice or to care for that you do not have to log in again for each page or see this popup again for each page.
As soon as you click on an external link or video, however, cookies may be set by the operators of these sites, which we cannot influence. Learn more on our privacy page.