Preventive effect of theanine intake on stress-induced impairments of hippocampal long-term potentiation and recognition memory

Theanine, γ-glutamylethylamide, is one of the major amino acid components in green tea. Based on the preventive effect of postnatal theanine intake on mild stress-induced attenuation of hippocampal CA1 long-term potentiation (LTP), the present study investigated the effect of postweaning theanine intake on stress-induced impairment of LTP and recognition memory.

Serum corticosterone levels were lower in theanine-administered rats than in control rats even after stress exposure. In addition, object recognition memory was impaired in control rats but not in theanine-administered rats. The present study indicates the preventive effect of theanine supplementation after weaning on stress-induced impairments in hippocampal LTP and recognition memory.

It is likely that the change in corticosterone secretion after theanine intake is involved in the preventive effect.


Brain Research Bulletin: Preventive effect of theanine intake on stress-induced impairments of hippocamapal long-term potentiation and recognition memory

Found at Alkohol adé (german)

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