Skip to content


Histamine is a tissue hormone. It is also widely distributed in the plant kingdom and in bacteria. Histamine is found almost everywhere in the human body, including in the skin, the lungs, the mucous membrane of the gastrointestinal tract and in the hypothalamus, a part of the brain.

It plays a central role in many normal and pathological reactions, especially inflammatory reactions and allergies. It is used by the immune system to defend itself against substances foreign to the body. Thus, it serves as one of the messenger substances in the inflammatory reaction to cause swelling of the tissue.

In the gastrointestinal tract, it plays an important role in the regulation of gastric acid production and motility, the mobility of the intestines. In the brain, it participates in the control of the sleep-wake rhythm and appetite control.

Biochemically, like serotonin, dopamine, adrenaline or noradrenaline, it is a biogenic amine. It is formed by splitting off carbon dioxide from the amino acid histidine.

Foods also contain appreciable histamine concentrations, e.g. strawberries, cheese, tuna, tomatoes, yeast, chocolate, red wine and sauerkraut. Histamine is produced by some plants as a defense agent (e.g., by stinging nettles).

Powered by BetterDocs

Close Popup

Bye bye booze needs a few cookies, too.

However, we try only to activate as few as possible technically necessary cookies so that your visit to this site cannot be tracked as far as possible by third parties. We do not share any information about your visit with anyone.

But even we we do need a few - e.g. to display this legal notice or to care for that you do not have to log in again for each page or see this popup again for each page.

As soon as you click on an external link or video, cookies may be set by the operators of these sites, which we cannot influence. Learn more on our privacy page.

Close Popup