Wernicke encephalopathy (WE) and Korsakoff psychosis (KP), collectively referred to as Wernicke-Korsakoff syndrome (WKS), are distinct but overlapping neuropsychiatric disorders associated with thiamine deficiency. Thiamine pyrophosphate, the biologically active form of thiamine, is essential for several biochemical pathways involved in carbohydrate utilization. Both genetic susceptibilities and acquired deficiencies resulting from alcoholic and nonalcoholic factors are…
