This study investigated the biological and clinical effects of N-acetyl-cysteine (NAC), the prodrug to L-cysteine, a precursor of the natural biological antioxidant glutathione, in patients with Parkinson's disease (PD). Forty-two patients with PD were randomized to receive either weekly intravenous infusions of NAC (50 mg/kg) plus oral doses (500 mg twice daily) for three months…
