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An antidepressant dose of taurine increases GABAA receptor α2 subunit and BDNF mRNA expression in the hippocampus of diabetic rats

 
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 BBB editorialteam
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Joined: 5 years ago
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Topic starter 04/02/2021 9:48 pm  

Diabetes mellitus is a metabolic disorder associated with an increased risk of depression. Diabetic rats exhibit depression-like behavior, and taurine, one of the most abundant free amino acids in the brain, reverses this depressive behavior. Because taurine is a GABAA agonist modulator, we hypothesize that its antidepressant effect results from interaction on this system by…



   
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antidepressant effect of depression Diabetes mellitus GABA GABA receptor
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Topic Tags:  antidepressant effect of (1) , depression (3) , Diabetes mellitus (1) , GABA (8) , GABA receptor (2) ,
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