The liver suffers in silence for a long time. When warning signs like fatigue, itching, or upper abdominal pressure appear, it’s often five minutes to midnight. Here, you’ll learn how liver cirrhosis develops, what stages there are—and what you can do to prevent it from getting that far.
By Bernd Guzek, MD, PhD
The liver is a vital organ. It filters toxins from the blood, helps with fat digestion, and produces important proteins. If it’s damaged over the long term, the tissue can scar—leading to liver cirrhosis, also called shrunken liver. This serious condition is the final stage of years of liver damage. Healthy liver tissue is gradually replaced by useless scar tissue. As a result, the liver loses its normal shape and function more and more—it shrinks and can’t properly handle tasks like blood cleansing, protein production, or nutrient storage.
What Is Liver Cirrhosis—Explained Briefly
The liver is a tough organ that can regenerate itself for a long time, but ongoing stress leads to irreversible damage. Liver cirrhosis can have many causes, such as viruses (e.g., hepatitis B or C), autoimmune diseases, or non-alcoholic fatty liver from obesity. But in western countries, excessive alcohol consumption is the most common trigger—up to 60 percent of cases are due to it.
Alcohol isn’t just a nerve poison; over time, it destroys liver cells that detoxify the body from alcohol. If someone regularly drinks too much (e.g., more than 20–40 grams of pure alcohol per day for women or 30–60 grams for men), fat first accumulates in the liver. This leads to inflammation where liver cells die off. The body tries to repair it by forming connective tissue—but this scar tissue increasingly narrows the vessels and hinders blood flow.
Early Warning Signs
For alcoholics who keep drinking despite warning signs, the damage progresses until cirrhosis develops. Not every drinker gets cirrhosis. Factors like genetics, diet, or additional illnesses play a role, but alcohol is the main culprit.
The development of alcohol-related liver cirrhosis happens in several stages. It starts harmlessly but can end fatally without intervention. Early warning signs can include fatigue, pressure in the right upper abdomen (below the right rib cage), itching, or a tendency to bruise easily.
Stages: From Fatty Liver to Cirrhosis
This is the first stage. The liver stores too much fat, triggered by alcohol. The liver swells, but often there are no symptoms yet—maybe just fatigue or mild upper abdominal pain. This stage is usually reversible.
Here, the liver cells become inflamed (hepatitis), and connective tissue forms (fibrosis). The liver hardens slowly. Symptoms may appear like yellowing of the skin (jaundice), loss of appetite, or exhaustion. The damage is still partially reversible if the trigger is stopped.
The final stage, where the liver is heavily scarred and shrunken. There are two sub-phases:
The compensated cirrhosis (the liver still functions reasonably well, often without severe symptoms) and the
decompensated cirrhosis (severe symptoms like fluid buildup in the abdomen (ascites), bleeding from enlarged veins (varices), confusion (hepatic encephalopathy), or jaundice). Here, the damage is no longer reversible, but progression can be slowed.
What Helps Now—By Stage
The earlier you act, the better the chances. The key is always: Stop the trigger!
For Fatty Liver: Immediate alcohol abstinence! The liver can regenerate within weeks to months. Additionally, a healthy diet (low fat, lots of fruits and vegetables), exercise, and weight loss if overweight help. A doctor can check this with ultrasound or blood tests.
For Early Cirrhosis (Fibrosis): Avoid alcohol completely if not already done—it’s crucial to prevent further damage. Medications against inflammation or to support liver function can help. Regular doctor check-ups (e.g., FibroScan to measure hardening) are important. Sometimes treatment for accompanying diseases is needed. Here, the fibrosis can still regress.
When Cirrhosis Is Established: Alcohol abstinence remains the top priority to at least delay complications. Treatment now targets symptoms: Diuretics for fluid retention, medications against bleeding or infections. Dietary changes (high-calorie, protein-rich) and vaccinations against hepatitis are advisable. In advanced cases, a liver transplant may be considered. Addiction counseling or detox programs can help stop alcohol consumption long-term.
Do Doctors Transplant a New Liver in Extreme Cases?
Sort of. In extreme cases, a liver transplant is the last resort. This happens when the liver completely fails and no other treatment helps—usually in the decompensated stage. But a prerequisite is absolute abstinence for at least six months, otherwise the donor organ would be damaged again immediately. The surgery replaces the sick liver with a donor liver (from deceased or living donors). Afterward, lifelong medications are needed to prevent rejection. Complete alcohol abstinence is absolutely necessary. The success rate is good, but waiting times for donor organs can be long.
What Is the End Stage of Liver Cirrhosis Like?
The end stage of liver cirrhosis is the decompensated phase, where the liver can no longer maintain its functions. Symptoms worsen: The abdomen swells with fluid (ascites), legs and feet retain water, skin and eyes turn yellow (jaundice), anemia occurs, confusion or coma (encephalopathy) from toxins in the brain. Bleeding often happens, e.g., from burst veins in the stomach or esophagus, which is life-threatening. Infections (e.g., peritonitis) or kidney failure are common.
Death usually doesn’t come suddenly but through complications: Often from massive internal bleeding, infections, multi-organ failure (e.g., liver and kidney failure), or liver cancer that can develop on cirrhosis. Without treatment, those affected in the end stage often survive only months to a few years. With good care and abstinence, life can be extended.
That’s why it’s important to seek help early—cirrhosis is preventable if you quit alcohol in time!
Frequently Asked Questions (FAQ)
Can the Liver Recover?
In early stages, yes—if the cause is consistently treated.
Late cirrhosis is usually not reversible, but often still stabilizable if caught in time.
What Do Affected People Often Die From?
From complications like massive bleeding, infections, liver/kidney failure, or liver cancer.
Early therapy improves the prognosis.
What Should I Do Immediately?
Stop drinking alcohol, get medical check-up soon, watch for warning signs—and accept support.
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Bernd Guzek, MD, PhD
Physician, Author, Affected Relative & Co-Founder of Bye Bye Booze
Has been working for many years on the biochemical foundations of addiction and brain metabolism disorders as well as their modulation by nutrients.