Sobriety Dictionary
Everything you need to know about living without alcohol in the Bye Bye Booze encyclopedia
Abram Hoffer
Abram Hoffer: Short Overview Abram Hoffer (1917–2009) was a Canadian psychiatrist and biochemist who played a decisive role in shaping…
Acetaldehyde – the highly toxic intermediate in alcohol metabolism in the body
Acetaldehyde is a highly reactive, toxic metabolite produced during alcohol breakdown. As soon as we drink ethanol, the liver begins…
Adenosine
Adenosine is a nucleoside consisting of adenine attached to a ribose sugar molecule, serving as a fundamental component in cellular…
Adenosine Receptors
Adenosine Receptors are a family of G-protein-coupled receptors that mediate the physiological effects of adenosine, a purine nucleoside involved in…
Adrenaline
Adrenaline is a hormone. It is an important neurotransmitter (nerve messenger) and belongs to the catecholamines. Our body forms it…
Alanine
Alanine is a non-essential amino acid, the body can produce it itself.
Alcohol dehydrogenase
Function of Alcohol Dehydrogenase in the Body Alcohol dehydrogenase first converts consumed alcohol into acetaldehyde – an intermediate stage that…
Alcoholic and Alcohol Use Disorder: The Current Medical Definition
In modern medical terminology, the term “alcoholic” has largely been replaced by more precise diagnostic labels such as Alcohol Use…
Amino acids
Amino acids are the components of life that make up proteins. Amino acids are found in all living organisms. A…
Amino acids
Amino acids are the components of life that make up proteins. Amino acids are found in all living organisms. A…
Ammonia
Ammonia is a sharp-smelling, colorless gas. In metabolism, ammonia is present as ammonium and plays a crucial role in the…
Amygdala: Key Role in Emotional Processing, Panic Disorders, and Alcoholism
The amygdala is a key brain structure involved in fear, anxiety, and emotional memory. Located deep within the temporal lobes,…
Aneurin
Other word for vitamin B1.
Anxiety Disorders
Anxiety Disorders are among the most common mental health conditions. They are characterized by individuals experiencing excessive, inappropriate, or persistent…
Anxiolytic
Anxiolytic means anxiety-relieving.
Arginine
Arginine is a semi-essential amino acid - meaning that often not enough of it is formed during the growth phase…
Arginine deficiency
Without arginine, the body cannot detoxify the ammonia that is constantly produced in the metabolism.Without arginine, the body cannot produce…
Ascorbate
Other word for ascorbic acid or vitamin C.
Ascorbic acid
Chemical name for vitamin C
Asparagine
Asparagine is a non-essential amino acid that the body uses to build proteins. In cell metabolism, asparagine can be produced…
Aspartate
Another name for aspartic acid. More information here.
Aspartic acid
Aspartic acid is a non-essential amino acid from which the body builds proteins.
Benzodiazepines
Benzodiazepines are a group of synthetic medications with sedative, anxiolytic, muscle-relaxant, and anticonvulsant effects. They are among the most commonly…
Beriberi
The cause of beriberi is a deficiency of vitamin B1 (thiamine). The body needs vitamin B1 to convert carbohydrates into…
Binge drinking
The term binge drinking can be translated as "intoxicated drinking". In media reporting, the word "binge drinking" is also frequently…
Blood Pressure And Alcohol
Blood Pressure & Alcohol: Multi-Stage Impact Alcohol consumption affects the cardiovascular system in a complex, multi-layered manner. In the short…
Calcium in Alcohol Withdrawal
Calcium in Alcohol Withdrawal – Why Levels Often Drop and Why Low Calcium Is Dangerous Calcium is not only important…
Catecholamines
Catecholamines are norepinephrine and dopamine (primary catecholamines) and epinephrine and its derivatives (secondary catecholamines). The body forms catecholamines from the…
Chromium
The heavy metal chromium is an essential trace element for the human body. A healthy adult needs less than one…
Cobalamin
Another word for vitamine B12
Cortisol
Cortisol is a hormone produced in the adrenal cortex. It belongs to the glucocorticoids and plays a pivotal role in…
Craving
Craving is the strong desire for a substance such as alcohol.
Cysteine
Cysteine is a sulfur-containing amino acid and a component of proteins. The amino acid serine is required for its assembly.…
Daily Alcohol Intake
Daily drinking guidelines describe ‘lower-risk’ limits for adults, not a safe or healthy target. Recommendations vary slightly between countries, yet…
Delirium tremens
Delirium tremens (DTs) is a life-threatening complication of alcohol withdrawal, characterized by severe confusion, hallucinations, and autonomic hyperactivity. It arises…
Dopamine
Dopamine is a nerve messenger, a neurotransmitter. It is a real all-rounder. It provides a feeling of rewarded satisfaction. At…
Dry-Drunk-Syndrome – unhappy sober alcoholics
"Dry Drunk Syndrome" refers to behaviors of sober alcoholics that still correspond to those of drinkers. These include depression, anxiety…
Electrolyte Imbalances in Liver Cirrhosis
In liver cirrhosis, the scarred liver impairs the body's ability to maintain electrolyte balance, leading to various imbalances. These electrolytes,…
Electrolytes
Electrolytes are minerals that exist in the body in dissolved form as electrically charged particles – either as positively charged…
Enzymes
Enzymes are giant biological molecules that act as catalysts to accelerate chemical reactions.
Epigenetic / Epigenetics
Epigenetics studies things that happen outside our DNA genetic material and are inherited. Excerpt from the book: "Alcoholism is heritable.…
Folic acid
The body needs folic acid to rebuild the genetic material. The body can only store 15 milligrams. Even if the…
GABA
GABA (gamma-aminobutyric acid) is the brain’s main inhibitory neurotransmitter. It is synthesised from glutamate, which is found in many protein-rich…
Glutamate
1 Glutamic acid, a nerve messenger, not to be confused with the flavor enhancer. 2. Glutamate, monosodium glutamate, a flavor…
Glutamic acid / glutamate
Chemists also call the natural neurotransmitter glutamate glutamic acid - the artificial flavor enhancer, on the other hand, monosodium glutamate.…
Glutamine
Glutamine is an amino acid. It supplies our body cells with fast energy - but leaves the blood sugar level…
Glycine
Glycine is the smallest and simplest amino acid. It acts in the nervous system as an inhibitory, relaxing messenger. In…
Hangover – explained
A hangover is caused by the interaction of alcohol metabolism, inflammatory responses, neurotransmitter imbalances, and fluid loss. Here you’ll find…
Hippocampus
The hippocampus is a key brain structure involved in memory formation, emotional regulation, and stress processing. The hippocampus is a…
Histamine
Histamine is a tissue hormone. It is also widely distributed in the plant kingdom and in bacteria. Histamine is found…
Histidine
Histidine is a semi-essential amino acid formed in the liver. Glutamic acid is formed when histidine is broken down. Histidine…
Holiday Heart Syndrome
Holiday Heart Syndrome (HHS) is an acute cardiac arrhythmia—most commonly atrial fibrillation—triggered by heavy alcohol consumption, typically during holidays or…
How Alcohol Sabotages Sleep and Becomes One of the Biggest Relapse Risks
How Alcohol Sabotages Sleep and Becomes One of the Biggest Relapse Risks Even after years of sobriety, chronically disrupted sleep…
Isoleucine
Isoleucine is an essential amino acid that the body cannot produce itself. It must therefore be supplied with food. The…
Jellinek, E.M.
E. M. Jellinek (Elvin Morton Jellinek, 1890–1963) was an American physiologist and addiction researcher widely regarded as the founder of…
Kindling Effect
What is the Kindling Effect? The kindling effect describes a progressive increase in the brain’s sensitivity to repeated withdrawal episodes…
Korsakow’s syndrome
Symptom of Korsakow's syndrome is memory loss. Both forgetting of old memory contents (retrograde amnesia) and inability to remember newly…
Leucine
Leucine is an essential amino acid that the body cannot produce itself. It must therefore be supplied with food. Leucine…
Liver Cirrhosis
Liver Cirrhosis refers to the end stage of various chronic liver diseases. Healthy liver tissue is gradually replaced by non-functional…
Lysine
Lysine represents an essential amino acid that the human body is unable to synthesize independently. It serves as a primary…
Magnesium in alcoholism and withdrawal
Magnesium plays a crucial role in alcohol withdrawal — functions, deficiency, bioavailability of different compounds. Magnesium is essential for the…
Manganese
The trace element manganese is a component of many enzymes, e.g. peroxidases, which break down hydrogen peroxide, which is dangerous…
Melanin
Melanins are dark brown to black or yellowish to reddish pigments (natural dyes) that cause the coloration of the skin,…
Melatonin
Melatonin is a hormone that the body produces from serotonin. It is a neurotransmitter. The hormone controls the day-night rhythm…
Methionine
Methionine is an essential, sulfur-containing amino acid that the body cannot produce itself and must therefore be ingested with food.…
Neuropathy, Alcohol-Related
Alcohol-related neuropathy is one of the most common physical consequences of long-term heavy alcohol consumption and mainly affects the nerves…
Neurotransmitter
Neurotransmitters (nerve messengers) transmit stimuli from one nerve cell to another nerve cell or cell, and can also amplify or…
Niacin: How it works to reduce cravings
Niacin (Vitamin B3), also referred to as nicotinic acid or niacinamide, is viewed in orthomolecular medicine as an adjunctive strategy…
Nitric Oxide
Nitric oxide is a molecule consisting of one oxygen and one nitrogen atom. It plays a crucial role in regulating…
Norepinephrine
Norepinephrine is a nerve messenger (neurotransmitter). It belongs to the group of catecholamines. The body needs the amino acids phenylalanine…
Norepinephrine (Noradrenaline) and Alcohol Use Disorder
Norepinephrine (also called noradrenaline) is a neurotransmitter and stress hormone produced in the brain (mainly in the locus coeruleus) and…
Pantothenic acid
Another word for vitamine B5.
Pellagra
Results from deficiency of vitamin B3.
Pernicious anemia
Results from vitamin B12 deficiency. You can find out more here.
Phenylalanine
Phenylalanine is an essential amino acid from which the body builds proteins. It is similar to alanine and must be…
Potassium
Potassium is an essential mineral and electrolyte. It is found mainly inside body cells and is crucial for the electrical…
Proline
Proline is a non-essential amino acid. Among other things, proline is needed in the human body for the formation of…
Pyridoxine
Vitamin B6. More here.
Relapse after alcohol dependence
Relapse, in the context of alcohol dependence, refers to resuming alcohol consumption after a period of abstinence or reduction. This…
Resveratrol
Resveratrol belongs to a group of compounds called polyphenols. They are thought to act like antioxidants, protecting the body from…
Riboflavin
Vitamin B2. You can find more information here.
Scurvy
Disease caused by a lack of vitamin C. You can find out more here.
Selenium
Selenium is a trace element. Selenium is essential for all forms of life - translated, this means that without the…
Serine
Serine is an essential amino acid from which the body forms proteins. Serine is a precursor in the production of…
Serotonin
Serotonin is a neurotransmitter, a chemical messenger. Serotonin is responsible for the feeling of happiness. If serotonin is missing, anxiety…
Sleep apnea
Sleep apnea is a disorder in which breathing repeatedly stops during sleep. These pauses in breathing can last just a…
Sleep Disturbances & Alcohol – the Vicious Cycle
Disrupted sleep poses one of the greatest long-term risks for alcohol relapse, even years after quitting. Unfortunately, prolonged alcohol abuse…
Sodium in Alcohol Withdrawal
Sodium in Alcohol Withdrawal – Why Imbalance Occurs and Why It Matters Sodium is the most important extracellular electrolyte and…
Strachan’s syndrome
Strachan syndrome is rare. According to current research, it is a deficiency disease, mainly caused by an undersupply of vitamin…
T3
Abbreviation for triiodothyronine. More information here.
T4
T4 is the abbreviation for the thyroid hormone thyroxine. You can find out more here.
Taurine
Like GABA, taurine is a protein building block, an amino acid. Unlike GABA, taurine is not a chemical messenger, but…
Thiamine
Chemical name for vitamin B1. You can find out more here.
Thiamine
Chemical name for vitamin B1. You can find out more here.
Thiamine Deficiency
Vitamin B1 deficiency. The body needs vitamin B1 to convert carbohydrates into energy. That is why a thiamine deficiency first…
Trace elements
Trace elements are inorganic nutrients that humans require only in very small amounts (traces). In contrast to the bulk elements,…
Triiodothyronine (T3)
Triiodothyronine (T3) is one of the two most important thyroid hormones. It is partly formed directly in the thyroid gland,…
Tryptophan
Tryptophan is an essential amino acid, which means that the body cannot produce it itself. Under normal conditions, the daily…
Tyrosine
Tyrosine is a non-essential amino acid; in principle, the body can build it itself from phenylalanine, which must be supplied…
Valine
Valine is an amino acid and an important component of many proteins. The human organism is not able to produce…
Vitamin A
Vitamin A refers to several chemical compounds that have biological functions in all mammals. They are partly ingested directly with…
Vitamin B1 – Thiamine
Thiamine (Vitamin B1), also known as the “anti-stress vitamin” or aneurin, is a water-soluble B-complex vitamin that plays an indispensable…
Vitamin B12
Vitamin B12 (cobalamin) is important for cell division and blood formation as well as for the function of the nervous…
Vitamin B2
Vitamin B2 (Riboflavin) is involved in many metabolic processes. These include the production of thyroid hormones, the production of energy…
Vitamin B3
Nicotinic acid (also: niacin) is a vitamin from the B-complex. Vitamin B3 is found in all living cells and is…
Vitamin B5
Vitamin B5 (pantothenic acid) strengthens the immune system, allows wounds to heal and also has a central role in the…
Vitamin B6
Vitamin B6 is a collective name for pyridoxine, pyridoxamine and pyridoxal. The body builds the so-called P5P (pyridoxal phosphate,) from…
Vitamin C
Vitamin C (ascorbic acid) is a colorless and odorless, crystalline, easily water-soluble solid with an acidic taste. Vitamin C performs…
Vitamin D
Vitamin D3 (cholecalciferol) is a fat-soluble vitamin. It can also be formed in the body with UVB radiation. This requires…
Vitamin E
Vitamin E (tocopherol) is a component of all cell walls. It acts there as a redox system, which means that…
Wernicke-Korsakow syndrome
Wernicke's encephalopathy (brain disease) is a disease of the central nervous system that is usually associated with chronic alcohol abuse…
Wernicke’s encephalopathy
Wernicke's encephalopathy is a degenerative disease of the brain in adults. It occurs in the presence of vitamin B1 deficiency.…
Willenbring, Mark
Dr. Mark Willenbring is an American psychiatrist and addiction researcher who fundamentally challenges the traditional view of alcohol dependence as…
Zinc
Zinc is a chemical element. It occurs more frequently on earth than copper or lead. Zinc is essential for all…